{"id":5281,"date":"2023-05-03T10:08:36","date_gmt":"2023-05-03T07:08:36","guid":{"rendered":"https:\/\/abomicspgx.com\/?page_id=5281"},"modified":"2024-01-16T14:22:57","modified_gmt":"2024-01-16T12:22:57","slug":"haittavaikutukset","status":"publish","type":"page","link":"https:\/\/abomicspgx.com\/fi\/laakareille\/tieteellinen-naytto\/haittavaikutukset\/","title":{"rendered":"Haittavaikutukset"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5281\" class=\"elementor elementor-5281\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-029255d elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-section-height-default\" data-id=\"029255d\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4636666\" data-id=\"4636666\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-a86621d elementor-section-full_width elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"a86621d\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;animation&quot;:&quot;fadeIn&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-d0f91c7\" data-id=\"d0f91c7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cacc496 elementor-widget elementor-widget-heading\" data-id=\"cacc496\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Haittavaikutusten ennaltaehk\u00e4isy<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-968a391 elementor-widget elementor-widget-heading\" data-id=\"968a391\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Farmakogeneettisen testin tulokset l\u00e4\u00e4kitys&amp;shyp\u00e4\u00e4t\u00f6ksenteon tukena<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-536aee1 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-heading\" data-id=\"536aee1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Laaja tutkimus osoittaa kliinisesti merkitt\u00e4vien haittavaikutusten v\u00e4henev\u00e4n 30 %, kun hoitavalla l\u00e4\u00e4k\u00e4rill\u00e4 on farmakogeneettisen testin tulokset l\u00e4\u00e4kitysp\u00e4\u00e4t\u00f6ksenteon tukena.<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0a9d56b elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-section-height-default\" data-id=\"0a9d56b\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-d231fdb\" data-id=\"d231fdb\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-14721f9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"14721f9\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-a097b6c\" data-id=\"a097b6c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1db0695 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"1db0695\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h2>Farmakogeneettisen testin avulla haittavaikutukset v\u00e4heniv\u00e4t 30 %<\/h2>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-00216a1\" data-id=\"00216a1\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-aac75b7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"aac75b7\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-9f727e6\" data-id=\"9f727e6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-113c635 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"113c635\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>L\u00e4\u00e4kkeiden aiheuttamat haittavaikutukset ja niiden hoitaminen kuluttavat terveydenhuollon resursseja ja aiheuttavat kustannuksia. Esimerkiksi Uudenmaan p\u00e4ivystyksess\u00e4 hoidetaan moninkertainen m\u00e4\u00e4r\u00e4 potilaita, joilla on henke\u00e4 uhkaava l\u00e4\u00e4kkeen haittavaikutus, kuin liikenneonnettomuuksissa vakavasti loukkaantuneita potilaita.<a href=\"#referenssit\"><sup>1, <\/sup><sup>2<\/sup><\/a><\/p><p>Laajan eurooppalaisen tutkimuksen mukaan farmakogeneettinen testi l\u00e4\u00e4kitysp\u00e4\u00e4t\u00f6ksenteon tukena v\u00e4hent\u00e4\u00e4 kliinisesti merkitt\u00e4vien haittavaikutusten m\u00e4\u00e4r\u00e4\u00e4 30 %.<a href=\"#referenssit\"><sup>3<\/sup><\/a> Tutkimukseen osallistui noin 7 000 potilasta, joita hoidettiin sairaalassa tai terveyskeskuksessa seitsem\u00e4ss\u00e4 Euroopan maassa. \u201dTutkimus osoittaa farmakogeneettisen testauksen olevan toteutettavissa erilaisissa eurooppalaisissa terveydenhuoltoj\u00e4rjestelmiss\u00e4 ja antaa vahvaa n\u00e4ytt\u00f6\u00e4 farmakogeneettisen testauksen hy\u00f6dyst\u00e4 l\u00e4\u00e4kkeiden haittavaikutuksien ehk\u00e4isyss\u00e4.\u201d<a href=\"#referenssit\"><sup>4<\/sup><\/a> Farmakogenetiikka vaikuttaa haittavaikutusriskin lis\u00e4ksi my\u00f6s hoidon tehoon, jota ei t\u00e4ss\u00e4 tutkimuksessa tarkasteltu, joten testaamisen kokonaishy\u00f6ty voi olla viel\u00e4 suurempi kuin mit\u00e4 tutkimus osoittaa.<a href=\"#referenssit\"><sup>4<\/sup><\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1fa4dfc elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-reverse-tablet elementor-section-height-default\" data-id=\"1fa4dfc\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ce8f6aa\" data-id=\"ce8f6aa\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8cfa9eb elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"8cfa9eb\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>[1] Kauppila, M. et al (2021) Incidence, preventability, and causality of adverse drug reactions at a university hospital emergency department. European Journal of Clinical Pharmacology. 77, 643-650. <a href=\"https:\/\/doi.org\/10.1007\/s00228-020-03043-3\">https:\/\/doi.org\/10.1007\/s00228-020-03043-3<\/a>\u00a0<\/p><p>[2] Suomen virallinen tilasto (SVT): Tieliikenneonnettomuustilasto [verkkojulkaisu]. ISSN=1798-758X. Helsinki: Tilastokeskus [Viitattu: 26.4.2023]. Saantitapa: <a href=\"https:\/\/stat.fi\/tilasto\/ton\">https:\/\/stat.fi\/tilasto\/ton<\/a>\u00a0 \/\u00a0<\/p><p>[3] Swen, J. (2023) A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study. The Lancet. 401(10374), 347-356. <a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(22)01841-4\">https:\/\/doi.org\/10.1016\/S0140-6736(22)01841-4<\/a>\u00a0<\/p><p>[4] Tornio, A. (2023) ERIKOISL\u00c4\u00c4K\u00c4RIN UUTISET Kliininen farmakologia ja l\u00e4\u00e4kehoito. L\u00e4\u00e4ketieteellinen Aikakauskirja Duodecim 139(6):427 <a href=\"https:\/\/www.duodecimlehti.fi\/duo17595\">https:\/\/www.duodecimlehti.fi\/duo17595<\/a>\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Haittavaikutusten ennaltaehk\u00e4isy Farmakogeneettisen testin tulokset l\u00e4\u00e4kitys&#038;shyp\u00e4\u00e4t\u00f6ksenteon tukena Laaja tutkimus osoittaa kliinisesti merkitt\u00e4vien haittavaikutusten v\u00e4henev\u00e4n 30 %, kun hoitavalla l\u00e4\u00e4k\u00e4rill\u00e4 on farmakogeneettisen testin tulokset l\u00e4\u00e4kitysp\u00e4\u00e4t\u00f6ksenteon tukena. Farmakogeneettisen testin avulla haittavaikutukset v\u00e4heniv\u00e4t 30 % L\u00e4\u00e4kkeiden aiheuttamat haittavaikutukset ja niiden hoitaminen kuluttavat terveydenhuollon resursseja ja aiheuttavat kustannuksia. Esimerkiksi Uudenmaan p\u00e4ivystyksess\u00e4 hoidetaan moninkertainen m\u00e4\u00e4r\u00e4 potilaita, joilla on henke\u00e4 uhkaava [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":706,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"content-type":"","_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"class_list":["post-5281","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages\/5281","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/comments?post=5281"}],"version-history":[{"count":16,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages\/5281\/revisions"}],"predecessor-version":[{"id":6658,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages\/5281\/revisions\/6658"}],"up":[{"embeddable":true,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages\/706"}],"wp:attachment":[{"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/media?parent=5281"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}