{"id":1978,"date":"2023-01-12T00:45:55","date_gmt":"2023-01-11T22:45:55","guid":{"rendered":"https:\/\/abomicspgx.com\/?page_id=1978"},"modified":"2024-01-12T11:05:00","modified_gmt":"2024-01-12T09:05:00","slug":"psykiatria","status":"publish","type":"page","link":"https:\/\/abomicspgx.com\/fi\/laakareille\/tieteellinen-naytto\/psykiatria\/","title":{"rendered":"Psykiatria"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1978\" class=\"elementor elementor-1978\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dbdabb9 elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-section-height-default\" data-id=\"dbdabb9\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1cb0e80\" data-id=\"1cb0e80\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-68b8a55 elementor-section-full_width elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"68b8a55\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;animation&quot;:&quot;fadeIn&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-64e7f02\" data-id=\"64e7f02\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b9002d6 elementor-widget elementor-widget-heading\" data-id=\"b9002d6\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Psykiatria<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c500b5 elementor-widget elementor-widget-heading\" data-id=\"3c500b5\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Farmakogenetiikka masennuksen hoidossa<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-be7aeac elementor-widget elementor-widget-heading\" data-id=\"be7aeac\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">K\u00e4yp\u00e4 Hoito -suositus toteaa, ett\u00e4 \"Farmakogeneettisen tiedon hy\u00f6dynt\u00e4minen lis\u00e4\u00e4 masennusl\u00e4\u00e4kehoidon tuloksellisuutta depression hoidossa.\" ja suosittelee farmakogeneettist\u00e4 testi\u00e4 kun potilaalla on l\u00e4\u00e4keresistentti depressio tai potilas kokee poikkeuksellisen voimakkaita l\u00e4\u00e4kehaittoja.<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f64cfc5 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"f64cfc5\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/abomicspgx.com\/wp-content\/uploads\/2023\/08\/Farmakogenetiikka-masennus.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Lataa esite<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b578bb9 elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-section-height-default\" data-id=\"b578bb9\" data-element_type=\"section\" id=\"first\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-03a1429\" data-id=\"03a1429\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1a2fa8b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1a2fa8b\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-7ac4599\" data-id=\"7ac4599\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8c213fd elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"8c213fd\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h2>Farmakogeneettisesti testatut masennuspotilaat saavuttavat remission 15\u201374 % todenn\u00e4k\u00f6isemmin kuin testaamattomat <a href=\"#referenssit\">\u2076<\/a><\/h2>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7c3ed98 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"7c3ed98\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Kun l\u00e4\u00e4k\u00e4ri tekee l\u00e4\u00e4kitysp\u00e4\u00e4t\u00f6ksen farmakogeneettisen testiraportin avulla, masennuspotilas saavuttaa remission 15\u201374 % todenn\u00e4k\u00f6isemmin kuin potilas, jonka l\u00e4\u00e4kitysp\u00e4\u00e4t\u00f6ksess\u00e4 ei hy\u00f6dynnet\u00e4 farmakogenetiikka. T\u00e4m\u00e4n osoittaa meta-analyysi, joka kattaa kymmenen satunnaistettua kontrolloitua tutkimusta, joissa oli yhteens\u00e4 2614 koehenkil\u00f6\u00e4, sek\u00e4 kolme sokkouttamatonta tutkimusta, joissa oli yhteens\u00e4 2153 koehenkil\u00f6\u00e4 (RR 1.41, 95 % CI = 1.15\u20131.74, P = 0.001). <a href=\"#referenssit\"><sup>6<\/sup><\/a><\/p><p>Psyykenl\u00e4\u00e4kkeiss\u00e4 on paljon l\u00e4\u00e4keaineita, joihin farmakogenetiikka vaikuttaa merkitt\u00e4v\u00e4sti.<a href=\"#referenssit\"><sup>2, 9<\/sup><\/a>. Suomen masennusl\u00e4\u00e4kekulutuksesta 60 % on sellaista, johon farmakogenetiikka vaikuttaa kliinisesti merkitt\u00e4v\u00e4sti. <a href=\"#referenssit\"><sup>1, <\/sup><sup>2<\/sup><\/a>. Essitalopraami on Suomen k\u00e4ytetyin masennusl\u00e4\u00e4ke, ja se metaboloituu mm. CYP2C19:n kautta <a href=\"#referenssit\"><sup>2, 3<\/sup><\/a>. Suomalaisista noin 60 % on kuitenkin tavallista nopeampia tai hitaampia CYP2C19-metaboloijia <a href=\"#referenssit\"><sup>4<\/sup><\/a>. Yli puolella suomalaisista essitalopraami poistuu siis elimist\u00f6st\u00e4 tavallista nopeammin tai hitaammin, mink\u00e4 vuoksi tavanomaisella annostuksella ei saavuteta riitt\u00e4v\u00e4\u00e4 tehoa tai haittavaikutusten riski kasvaa.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-badac15\" data-id=\"badac15\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-6cd3fd5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6cd3fd5\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-1f852a1\" data-id=\"1f852a1\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4532f26 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"4532f26\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Farmakogeneettisell\u00e4 testill\u00e4 selvitet\u00e4\u00e4n potilaan l\u00e4\u00e4kitykseen vaikuttavat geenivariantit, ja testin lausuntoraporttia voi k\u00e4ytt\u00e4\u00e4 p\u00e4\u00e4t\u00f6ksenteon tukena l\u00e4\u00e4kityst\u00e4 ja sen annostusta valittaessa. Farmakogeneettinen testaaminen tutkitusti parantaa hoitotuloksia etenkin vaikea-asteista masennusta sairastavilla potilailla, mutta testaamisesta on havaittu olevan hy\u00f6ty\u00e4 my\u00f6s keskivaikeasta masennuksesta tai ahdistuneisuush\u00e4iri\u00f6st\u00e4 k\u00e4rsiville <a href=\"#referenssit\"><sup>5<\/sup><\/a>.<\/p><p>Farmakogeneettisen testin avulla l\u00e4\u00e4k\u00e4ri pystyy rajaamaan l\u00e4\u00e4kevaihtoehdoista pois sellaiset, jotka eiv\u00e4t potilaalla tehoaisi, ja toisaalta m\u00e4\u00e4r\u00e4\u00e4m\u00e4\u00e4n annoksen, joka on juuri kyseiselle potilaalle sopiva. T\u00e4m\u00e4 helpottaa l\u00e4\u00e4k\u00e4rin p\u00e4\u00e4t\u00f6ksentekoa ja voi nopeuttaa sopivan l\u00e4\u00e4kityksen l\u00f6ytymist\u00e4. My\u00f6s hoitomy\u00f6ntyvyys voi parantua, kun potilaalle ei kerry negatiivisia kokemuksia tehottomista tai haittavaikutuksia aiheuttavista l\u00e4\u00e4kkeist\u00e4 sek\u00e4 toistuvista l\u00e4\u00e4kitysmuutoksista.<\/p><p><strong>K\u00e4yp\u00e4 Hoito<\/strong> -suositus toteaa, ett\u00e4 farmakogeneettisen tiedon hy\u00f6dynt\u00e4minen lis\u00e4\u00e4 masennusl\u00e4\u00e4kehoidon tuloksellisuutta depression hoidossa. Potilaat, joilla on joko l\u00e4\u00e4keresistentti depressio tai poikkeuksellisen voimakkaita l\u00e4\u00e4kehaittoja on perusteltua testata. Farmakogenetiikkaa voi my\u00f6s hy\u00f6dynt\u00e4\u00e4 jos potilaan kokemat haittavaikutukset ovat luonteeltaan ep\u00e4tyypillisi\u00e4 tai jos ne tulevat jo pienell\u00e4 annoksella. <a href=\"#referenssit\"><sup>K\u00e4yp\u00e4 Hoito<\/sup><\/a> Ruotsin lapsi- ja nuorisopsykiatriset suositukset indikoivat farmakogeneettisen testauksen harkitsemista hoitoresistentiss\u00e4 depressiossaille<a href=\"#referenssit\"><sup>10<\/sup><\/a>.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1f8cbf4 elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-section-height-default\" data-id=\"1f8cbf4\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7fe23a9\" data-id=\"7fe23a9\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c041c74 elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"c041c74\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Farmakogenetiikan k\u00e4ytt\u00f6 on kustannusvaikuttavaa depressiopotilaiden hoidossa<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ce23a4e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ce23a4e\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-1a47cc2\" data-id=\"1a47cc2\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bc14ead elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"bc14ead\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Lukuisat tutkimukset osoittavat farmakogenetiikan olevan kustannusvaikuttavaa masennuksen hoidossa <a href=\"#referenssit\"><sup>8<\/sup><\/a>. Yhdysvaltalaistutkimuksessa havaittiin, ett\u00e4 farmakogeneettinen testaaminen mielenterveyspotilaiden hoidossa tuo merkitt\u00e4vi\u00e4 s\u00e4\u00e4st\u00f6j\u00e4 v\u00e4hentynein\u00e4 p\u00e4ivystysk\u00e4yntein\u00e4 sek\u00e4 sairaalahoitojaksoina. Puolen vuoden seurantajaksolla saavutettiin n. 2 000 \u20ac\u00a0 s\u00e4\u00e4st\u00f6t tavanomaiseen hoitopolkuun verrattuna ($1,948, SE $611, P &lt; 0.0001, N=817). <a href=\"#referenssit\"><sup>7<\/sup><\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-367e02b\" data-id=\"367e02b\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-23a6eef elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"23a6eef\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-cfb79b0\" data-id=\"cfb79b0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-011951d elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"011951d\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Erikoissairaanhoidon kuormitusta voi siis kevent\u00e4\u00e4 k\u00e4ytt\u00e4m\u00e4ll\u00e4 farmakogenetiikkaa hyv\u00e4ksi jo perusterveydenhuollossa. Teknologian kehitys on tuonut geenitestaamisen hintaa huomattavasti alasp\u00e4in viimeisen vuosikymmenen aikana. Farmakogeneettinen testaaminen onkin nyky\u00e4\u00e4n edullista: testi vastaa hinnaltaan yhden p\u00e4ivystysk\u00e4ynnin kustannuksia. Vastaavasti ty\u00f6terveyshuollossa investointi farmakogeneettiseen testiin maksaa itsens\u00e4 takaisin, kun ty\u00f6ntekij\u00e4n sairauspoissaolo lyhenee muutamalla p\u00e4iv\u00e4ll\u00e4.<\/p><p>Testin lausuntoraportti on laadittu mm. psykiatrien sek\u00e4 yleis- ja ty\u00f6terveysl\u00e4\u00e4k\u00e4reiden k\u00e4ytt\u00f6\u00f6n ja raportti tarjoaa l\u00e4\u00e4k\u00e4rin p\u00e4\u00e4t\u00f6ksenteon tueksi selke\u00e4t potilaskohtaiset suositukset eri l\u00e4\u00e4kkeiden k\u00e4yt\u00f6st\u00e4 ja annostuksesta.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8dbe73a elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-reverse-tablet elementor-section-height-default\" data-id=\"8dbe73a\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-31e8d9c\" data-id=\"31e8d9c\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0aeba3d elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"0aeba3d\" data-element_type=\"widget\" id=\"referenssit\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>[1] L\u00e4\u00e4kealan turvallisuus- ja kehitt\u00e4miskeskus Fimea &amp; Kansanel\u00e4kelaitos. (2022) Suomen l\u00e4\u00e4ketilasto 2021. Helsinki. <a href=\"https:\/\/urn.fi\/URN:NBN:fi-fe2022121672023\" target=\"_blank\" rel=\"noopener\">https:\/\/urn.fi\/URN:NBN:fi-fe2022121672023<\/a><br \/>[2] Abomics GeneRx-tietokanta <a href=\"https:\/\/www.terveysportti.fi\/apps\/generx\/\" target=\"_blank\" rel=\"noopener\">https:\/\/www.terveysportti.fi\/apps\/generx\/<\/a><br \/>[3] Sangkuhl, K., Klein T., and Altman R. (2011) PharmGKB summary: citalopram pharmacokinetics pathway. Pharmacogenetics and genomics. <a href=\"http:\/\/dx.doi.org\/10.1097%2FFPC.0b013e328346063f\" target=\"_blank\" rel=\"noopener\">http:\/\/dx.doi.org\/10.1097%2FFPC.0b013e328346063f<\/a><br \/>[4] H\u00e4kkinen, K. et al. (2022) Implementation of CYP2D6 copy-number imputation panel and frequency of key pharmacogenetic variants in Finnish individuals with a psychotic disorder. The Pharmacogenomics Journal. 22, 166-172. <a href=\"https:\/\/doi.org\/10.1038\/s41397-022-00270-y\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1038\/s41397-022-00270-y<\/a><br \/>[5] Bradley, P. et al. (2018) Improved efficacy with targeted pharmacogenetic-guided treatment of patients with depression and anxiety: A randomized clinical trial demonstrating clinical utility. Journal of Psychiatric Research. 96, 100-107. <a href=\"https:\/\/doi.org\/10.1016\/j.jpsychires.2017.09.024\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1016\/j.jpsychires.2017.09.024<\/a><br \/>[6] Brown, L. C. et al. (2022). Pharmacogenomic Testing and Depressive Symptom Remission: A Systematic Review and Meta\u2010Analysis of Prospective, Controlled Clinical Trials. Clinical Pharmacology &amp; Therapeutics. <a href=\"https:\/\/doi.org\/10.1002\/cpt.2748\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1002\/cpt.2748<\/a><br \/>[7] Perlis, R. et al. (2018) Pharmacogenetic testing among patients with mood and anxiety disorders is associated with decreased utilization and cost: A propensity-score matched study. Depression and Anxiety. 35(10), 946-952. <a href=\"https:\/\/doi.org\/10.1002\/da.22742\">https:\/\/doi.org\/10.1002\/da.22742<\/a><br \/>[8] Morris, Sarah A. et al. (2022) Cost effectiveness of pharmacogenetic testing for drugs with Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines: a systematic review.\u202fClinical Pharmacology &amp; Therapeutics.\u202f<a href=\"https:\/\/doi.org\/10.1002\/cpt.2754\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1002\/cpt.2754<\/a><br \/>[9] Milosavljevi\u0107, F. et al (2021). Association of CYP2C19 and CYP2D6 poor and intermediate metabolizer status with antidepressant and antipsychotic exposure: a systematic review and meta-analysis. JAMA psychiatry, 78(3), 270-280. <a href=\"https:\/\/doi.org\/10.1001\/jamapsychiatry.2020.3643\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1001\/jamapsychiatry.2020.3643<\/a><br \/>[10] Kunskapsst\u00f6d f\u00f6r barn- och ungdomspsykiatrisk l\u00e4kemedelsbehandling inom BUP Stockholm (2023) Barn- och ungdomspsykiatri Region Stockholm https:\/\/www.bup.se\/494342\/contentassets\/c5b865fe86d44fbd957c9d71eaaeadbe\/farmakainstruktion-bup-stockholm.pdf<br \/>[K\u00e4yp\u00e4 Hoito] Depressio. K\u00e4yp\u00e4 hoito -suositus. Suomalaisen L\u00e4\u00e4k\u00e4riseuran Duodecimin ja Suomen Psykiatriyhdistys ry:n asettama ty\u00f6ryhm\u00e4. Helsinki: Suomalainen L\u00e4\u00e4k\u00e4riseura Duodecim, 2023, <a href=\"http:\/\/www.kaypahoito.fi\/hoi50023#s13_2\" target=\"_blank\" rel=\"noopener\">www.kaypahoito.fi\/hoi50023#s13_2<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c215f18 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"c215f18\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-451eac2\" data-id=\"451eac2\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-74fee30 elementor-widget elementor-widget-template\" data-id=\"74fee30\" data-element_type=\"widget\" data-widget_type=\"template.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-template\">\n\t\t\t\t\t<div data-elementor-type=\"section\" data-elementor-id=\"2785\" class=\"elementor elementor-2785\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-521d690e elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-section-height-default\" data-id=\"521d690e\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-51ff24f4\" data-id=\"51ff24f4\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7eec952e elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"7eec952e\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Farmakogeneettisen testin tulokset kliinikolle tarkoitettuna lausuntoraporttina <\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-3a248b06 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3a248b06\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-1fdbe74a\" data-id=\"1fdbe74a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eb917cf elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"eb917cf\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Farmakogenetiikkaan liittyv\u00e4n tutkimustiedon m\u00e4\u00e4r\u00e4 on suuri ja kasvaa koko ajan. Kliinisen ty\u00f6n ohella voi olla vaikeaa pysy\u00e4 ajan tasalla uusista tieteellisist\u00e4 tutkimuksista. Sen vuoksi Abomicsin farmakogeneettinen raportti kokoaakin yhteen kliinikon kannalta oleellisen farmakogeneettisen tiedon l\u00e4\u00e4keaineiden k\u00e4ytt\u00f6- ja annostussuosituksina. Abomicsin farmakogenetiikan asiantuntijal\u00e4\u00e4k\u00e4rit seuraavat jatkuvasti alan uusimpia tutkimustuloksia ja p\u00e4ivitt\u00e4v\u00e4t suosituksia niiden mukaisesti, jotta sinulla on aina k\u00e4yt\u00f6ss\u00e4si tuoreimpiin tutkimuksiin perustuvat suositukset \u2013 ilman tarvetta k\u00e4yd\u00e4 itse l\u00e4pi kaikkia aiheeseen liittyvi\u00e4 tieteellisi\u00e4 artikkeleita.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7af6023c\" data-id=\"7af6023c\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-42ca9a50 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"42ca9a50\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-563af9fc\" data-id=\"563af9fc\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-635ae270 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"635ae270\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Farmakogeneettisen raportin suositukset perustuvat Abomicsin l\u00e4\u00e4ketieteellisten neuvonantajien ker\u00e4\u00e4mien tietojen synteesiin. Tietol\u00e4hteit\u00e4 ovat laadukkaat, julkaistut ja siteerattavat tieteelliset artikkelit, FDA:n (U.S. Food and Drug Administration) luettelo farmakogeneettisist\u00e4 biomarkkereista, jotka esiintyv\u00e4t l\u00e4\u00e4ke-etiketeiss\u00e4, l\u00e4\u00e4kkeiden valmisteyhteenvedot (SPC) sek\u00e4 CPIC:n (<a href=\"https:\/\/cpicpgx.org\/\" target=\"_blank\" rel=\"noopener\">Clinical Pharmacogenetics Implementation Consortium<\/a>) ja DPWG:n (<a href=\"https:\/\/www.pharmgkb.org\/page\/dpwg\" target=\"_blank\" rel=\"noopener\">Dutch Pharmacogenetics Working Group<\/a>) antamat suositukset. Kunkin potilaan l\u00e4\u00e4keannostelun kliininen p\u00e4\u00e4t\u00f6ksenteko on hoitavan l\u00e4\u00e4k\u00e4rin vastuulla.<\/p><p>Abomicsin farmakogeneettisess\u00e4 lausuntoraportissa on potilaan fenotyyppeihin perustuvat annostussuositukset yli 100 l\u00e4\u00e4keaineelle. Olemme laatineet raportin erityisesti esim. psykiatrien sek\u00e4 yleis- ja ty\u00f6terveysl\u00e4\u00e4k\u00e4reiden k\u00e4ytt\u00f6\u00f6n eik\u00e4 se edellyt\u00e4 perinn\u00f6llisyysl\u00e4\u00e4ketieteellist\u00e4 konsultaatiota. Lausuntoraporttia on helppo k\u00e4ytt\u00e4\u00e4 l\u00e4\u00e4kitysp\u00e4\u00e4t\u00f6ksentekosi tukena lyhyell\u00e4kin vastaanottok\u00e4ynnill\u00e4. Raportissa on yhteenvetolista l\u00e4\u00e4keaineista, joiden tehoon ja turvallisuuteen potilaan fenotyyppiarvio vaikuttaa merkitt\u00e4v\u00e4sti tai kohtalaisen merkitt\u00e4v\u00e4sti sek\u00e4 k\u00e4yt\u00e4nn\u00f6n suositukset l\u00e4\u00e4kkeen k\u00e4yt\u00f6st\u00e4 juuri kyseisen potilaan fenotyyppiarviolle. Digitaalisesta raportista l\u00f6yd\u00e4t helposti potilaskohtaiset annossuositukset l\u00e4\u00e4keaineen nimell\u00e4.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-21fd01c0 elementor-widget__width-initial jedv-enabled--yes elementor-invisible elementor-widget elementor-widget-button\" data-id=\"21fd01c0\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/abomicspgx.com\/wp-content\/uploads\/2023\/02\/B-Farma-D-malliraportti.pdf\" target=\"_blank\" download=\"\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Lataa malliraportti<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9621a7e elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-reverse-mobile elementor-reverse-tablet jedv-enabled--yes elementor-section-height-default\" data-id=\"9621a7e\" data-element_type=\"section\" id=\"lausuntoraportti-potilastietojarjestelmissa\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-a6e2ced elementor-invisible\" data-id=\"a6e2ced\" data-element_type=\"column\" data-settings=\"{&quot;animation&quot;:&quot;fadeIn&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-34d81e1 elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"34d81e1\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Farmakogeneettinen lausuntoraportti potilastietoj\u00e4rjestelm\u00e4ss\u00e4<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f031bce elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"f031bce\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Farmakogeneettisen testin tulokset n\u00e4kyv\u00e4t potilastietoj\u00e4rjestelm\u00e4ss\u00e4 vastaavalla tavalla kuin muidenkin laboratoriotestien tulokset. Tekstimuotoisen tulosyhteenvedon alussa on linkki ja PIN-koodi, joiden avulla saa avattua lausunnon, jossa on l\u00e4\u00e4kekohtaiset suositukset.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-c5ec7cb\" data-id=\"c5ec7cb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-19c5508 elementor-widget elementor-widget-video\" data-id=\"19c5508\" data-element_type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/www.youtube.com\\\/watch?v=Blf7Q5pYg9E&amp;t=80s&quot;,&quot;modestbranding&quot;:&quot;yes&quot;,&quot;start&quot;:80,&quot;show_image_overlay&quot;:&quot;yes&quot;,&quot;image_overlay&quot;:{&quot;url&quot;:&quot;https:\\\/\\\/abomicspgx.com\\\/wp-content\\\/uploads\\\/2023\\\/01\\\/Abomics-Raportin-avaus-5.png&quot;,&quot;id&quot;:3209,&quot;size&quot;:&quot;&quot;,&quot;alt&quot;:&quot;&quot;,&quot;source&quot;:&quot;library&quot;},&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t\t\t<div class=\"elementor-custom-embed-image-overlay\" style=\"background-image: url(https:\/\/abomicspgx.com\/wp-content\/uploads\/2023\/01\/Abomics-Raportin-avaus-5.png);\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-custom-embed-play\" role=\"button\" aria-label=\"Katso video\" tabindex=\"0\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"eicon-play\"><\/i>\t\t\t\t\t\t\t<span class=\"elementor-screen-only\">Katso video<\/span>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c4f7e82 elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-reverse-mobile elementor-reverse-tablet jedv-enabled--yes elementor-section-height-default\" data-id=\"c4f7e82\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-c4f6a00 elementor-invisible\" data-id=\"c4f6a00\" data-element_type=\"column\" data-settings=\"{&quot;animation&quot;:&quot;fadeIn&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-532388a elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"532388a\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Milloin farmakogeneettisest\u00e4 testist\u00e4 on hy\u00f6ty\u00e4?<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-9f5f819 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9f5f819\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-11af99b\" data-id=\"11af99b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7dc8d1e elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"7dc8d1e\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Kun teet l\u00e4\u00e4kitysp\u00e4\u00e4t\u00f6st\u00e4, voit tarkastaa vaikuttaako farmakogenetiikka kliinisesti merkitt\u00e4v\u00e4sti harkitsemaasi l\u00e4\u00e4kkeeseen <a href=\"https:\/\/www.terveysportti.fi\/apps\/laake\/\" target=\"_blank\" rel=\"noopener\">Duodecimin L\u00e4\u00e4ketietokannan Farmakogenetiikka -osiosta<\/a> tai\u00a0<a href=\"https:\/\/www.terveysportti.fi\/apps\/generx\/\" target=\"_blank\" rel=\"noopener\">Terveysportin Farmakogenetiikka -sovelluksesta<\/a> . <\/p><p>Jos k\u00e4yt\u00f6ss\u00e4si on Tietoevryn Lifecare-potilastietoj\u00e4rjestelm\u00e4n versio, joka sis\u00e4lt\u00e4\u00e4 Farmakogenetiikka-ominaisuuden, n\u00e4et l\u00e4\u00e4kkeen valittuasi punaisen tai keltaisen symbolin, jos farmakogenetiikan vaikutus on kliinisesti merkitt\u00e4v\u00e4 k.o. l\u00e4\u00e4kkeen kohdalla. Kysy lis\u00e4\u00e4 Lifecare-p\u00e4\u00e4k\u00e4ytt\u00e4j\u00e4lt\u00e4nne.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7c4e5ba\" data-id=\"7c4e5ba\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-63a1482 elementor-widget elementor-widget-video\" data-id=\"63a1482\" data-element_type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/www.youtube.com\\\/watch?v=Blf7Q5pYg9E&quot;,&quot;modestbranding&quot;:&quot;yes&quot;,&quot;show_image_overlay&quot;:&quot;yes&quot;,&quot;image_overlay&quot;:{&quot;url&quot;:&quot;https:\\\/\\\/abomicspgx.com\\\/wp-content\\\/uploads\\\/2023\\\/01\\\/Abomics-essitalopraami-farmakogenetiikka-2-scaled-e1675377802185.jpg&quot;,&quot;id&quot;:4198,&quot;size&quot;:&quot;&quot;,&quot;alt&quot;:&quot;&quot;,&quot;source&quot;:&quot;library&quot;},&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t\t\t<div class=\"elementor-custom-embed-image-overlay\" style=\"background-image: url(https:\/\/abomicspgx.com\/wp-content\/uploads\/2023\/01\/Abomics-essitalopraami-farmakogenetiikka-2-scaled-e1675377802185.jpg);\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-custom-embed-play\" role=\"button\" aria-label=\"Katso video\" tabindex=\"0\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"eicon-play\"><\/i>\t\t\t\t\t\t\t<span class=\"elementor-screen-only\">Katso video<\/span>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5c02b2c elementor-section-height-min-height elementor-section-full_width elementor-section-items-stretch elementor-reverse-tablet elementor-section-height-default\" data-id=\"5c02b2c\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-3d7aaa0\" data-id=\"3d7aaa0\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ff70bb3 elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"ff70bb3\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Farmakogeneettisen testin saatavuus <\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-11ac07a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"11ac07a\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-364653b\" data-id=\"364653b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c761d9c jedv-enabled--yes elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"c761d9c\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Farmakogeneettinen testi tehd\u00e4\u00e4n tavallisesta EDTA-verin\u00e4ytteest\u00e4, ja se on tilattavissa koodilla B-Farma-D tai B-FarmL-D.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-73883b0 elementor-widget__width-initial jedv-enabled--yes elementor-invisible elementor-widget elementor-widget-button\" data-id=\"73883b0\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/abomicspgx.com\/fi\/laakareille\/testin-saatavuus\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Lue lis\u00e4\u00e4 testin saatavuudesta<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2019c32\" data-id=\"2019c32\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-347e20c elementor-widget elementor-widget-spacer\" data-id=\"347e20c\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Psykiatria Farmakogenetiikka masennuksen hoidossa K\u00e4yp\u00e4 Hoito -suositus toteaa, ett\u00e4 &#8221;Farmakogeneettisen tiedon hy\u00f6dynt\u00e4minen lis\u00e4\u00e4 masennusl\u00e4\u00e4kehoidon tuloksellisuutta depression hoidossa.&#8221; ja suosittelee farmakogeneettist\u00e4 testi\u00e4 kun potilaalla on l\u00e4\u00e4keresistentti depressio tai potilas kokee poikkeuksellisen voimakkaita l\u00e4\u00e4kehaittoja. Lataa esite Farmakogeneettisesti testatut masennuspotilaat saavuttavat remission 15\u201374 % todenn\u00e4k\u00f6isemmin kuin testaamattomat \u2076 Kun l\u00e4\u00e4k\u00e4ri tekee l\u00e4\u00e4kitysp\u00e4\u00e4t\u00f6ksen farmakogeneettisen testiraportin avulla, masennuspotilas saavuttaa remission [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":706,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"content-type":"","_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"class_list":["post-1978","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages\/1978","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/comments?post=1978"}],"version-history":[{"count":155,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages\/1978\/revisions"}],"predecessor-version":[{"id":6609,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages\/1978\/revisions\/6609"}],"up":[{"embeddable":true,"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/pages\/706"}],"wp:attachment":[{"href":"https:\/\/abomicspgx.com\/fi\/wp-json\/wp\/v2\/media?parent=1978"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}